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Nicotinamide adenine dinucleotides and their precursor NMN have no direct effect on microtubule dynamics in purified brain tubulin

Microtubules are dynamic cytoskeletal polymers that provide mechanical support for cellular structures, and play important roles in cell division, migration, and intracellular transport. Their intrinsic dynamic instability, primarily controlled by polymerization-dependent GTP hydrolysis, allows for...

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Detalles Bibliográficos
Autores principales: Luchniak, Anna, Mahamdeh, Mohammed, Howard, Jonathon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6687165/
https://www.ncbi.nlm.nih.gov/pubmed/31393939
http://dx.doi.org/10.1371/journal.pone.0220794