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Insulin Receptor Substrate-1 (IRS-1) and IRS-2 expression levels are associated with prognosis in non-small cell lung cancer (NSCLC)

The insulin-like growth factor-1 (IGF-1) signaling pathway has been implicated in non-small cell lung cancer (NSCLC) outcomes and resistance to targeted therapies. However, little is known regarding the molecular mechanisms by which this pathway contributes to the biology of NSCLC. The insulin recep...

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Detalles Bibliográficos
Autores principales: Piper, Andrew J., Clark, Jennifer L., Mercado-Matos, Jose, Matthew-Onabanjo, Asia N., Hsieh, Chung-Cheng, Akalin, Ali, Shaw, Leslie M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6687170/
https://www.ncbi.nlm.nih.gov/pubmed/31393907
http://dx.doi.org/10.1371/journal.pone.0220567