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Atg11 tethers Atg9 vesicles to initiate selective autophagy

Autophagy recycles cytoplasmic components by sequestering them in double membrane–surrounded autophagosomes. The two proteins Atg11 and Atg17 are scaffolding components of the Atg1 kinase complex. Atg17 recruits and tethers Atg9-donor vesicles, and the corresponding Atg1 kinase complex induces the f...

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Detalles Bibliográficos
Autores principales: Matscheko, Nena, Mayrhofer, Peter, Rao, Yijian, Beier, Viola, Wollert, Thomas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6687201/
https://www.ncbi.nlm.nih.gov/pubmed/31356628
http://dx.doi.org/10.1371/journal.pbio.3000377