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The host cell secretory pathway mediates the export of Leishmania virulence factors out of the parasitophorous vacuole

To colonize phagocytes, Leishmania subverts microbicidal processes through components of its surface coat that include lipophosphoglycan and the GP63 metalloprotease. How these virulence glycoconjugates are shed, exit the parasitophorous vacuole (PV), and traffic within host cells is poorly understo...

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Detalles Bibliográficos
Autores principales: Arango Duque, Guillermo, Jardim, Armando, Gagnon, Étienne, Fukuda, Mitsunori, Descoteaux, Albert
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6687203/
https://www.ncbi.nlm.nih.gov/pubmed/31356625
http://dx.doi.org/10.1371/journal.ppat.1007982