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The host cell secretory pathway mediates the export of Leishmania virulence factors out of the parasitophorous vacuole
To colonize phagocytes, Leishmania subverts microbicidal processes through components of its surface coat that include lipophosphoglycan and the GP63 metalloprotease. How these virulence glycoconjugates are shed, exit the parasitophorous vacuole (PV), and traffic within host cells is poorly understo...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2019
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6687203/ https://www.ncbi.nlm.nih.gov/pubmed/31356625 http://dx.doi.org/10.1371/journal.ppat.1007982 |