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Protective Effects of 5-HT1A Receptor Inhibition and 5-HT2A Receptor Stimulation Against Streptozotocin-Induced Apoptosis in the Hippocampus

INTRODUCTION: Intracerebroventricular administration of streptozotocin (icv-STZ) induced apoptosis changes in neurons similar to Alzheimer’s disease. The serotonergic system via its receptor involved in survival of neurons. The present study examined the ability of selective 5-HT1A receptor antagoni...

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Detalles Bibliográficos
Autores principales: Shahidi, Siamak, Hashemi-Firouzi, Nasrin, Afshar, Simin, Asl, Sara Soleimani, Komaki, Alireza
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Penerbit Universiti Sains Malaysia 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6687217/
https://www.ncbi.nlm.nih.gov/pubmed/31447607
http://dx.doi.org/10.21315/mjms2019.26.2.5