Cargando…
Overexpression of human Atp13a2(Isoform-1) protein protects cells against manganese and starvation-induced toxicity
Mutations in ATP13A2 cause Kufor-Rakeb syndrome (KRS), a juvenile form of Parkinson’s disease (PD) with dementia. However, the mechanisms by which mutations in ATP13A2 cause KRS is not understood. The mutations lead to misfolding of the translated Atp13a2 protein and its premature degradation in the...
| Autores principales: | , , , , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2019
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6687281/ https://www.ncbi.nlm.nih.gov/pubmed/31393918 http://dx.doi.org/10.1371/journal.pone.0220849 |