State biomarkers for Machado Joseph disease: Validation, feasibility and responsiveness to change

Machado-Joseph disease (SCA3/MJD) is the most common spinocerebellar ataxia worldwide, and particularly so in Southern Brazil. Due to an expanded polyglutamine at ataxin-3, SCA3/MJD presents a relentless course with no current disease modifying treatment. Clinical scales used to measure SCA3/MJD pro...

Descripción completa

Detalles Bibliográficos
Autores principales: Furtado, Gabriel Vasata, de Oliveira, Camila Maria, Bolzan, Gabriela, Saute, Jonas Alex Morales, Saraiva-Pereira, Maria Luiza, Jardim, Laura Bannach
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Sociedade Brasileira de Genética 2019
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6687346/
https://www.ncbi.nlm.nih.gov/pubmed/31188927
http://dx.doi.org/10.1590/1678-4685-GMB-2018-0103

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6687346/
https://www.ncbi.nlm.nih.gov/pubmed/31188927
http://dx.doi.org/10.1590/1678-4685-GMB-2018-0103

Ejemplares similares