BOADICEA: a comprehensive breast cancer risk prediction model incorporating genetic and nongenetic risk factors

PURPOSE: Breast cancer (BC) risk prediction allows systematic identification of individuals at highest and lowest risk. We extend the Breast and Ovarian Analysis of Disease Incidence and Carrier Estimation Algorithm (BOADICEA) risk model to incorporate the effects of polygenic risk scores (PRS) and...

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Detalles Bibliográficos
Autores principales: Lee, Andrew, Mavaddat, Nasim, Wilcox, Amber N., Cunningham, Alex P., Carver, Tim, Hartley, Simon, Babb de Villiers, Chantal, Izquierdo, Angel, Simard, Jacques, Schmidt, Marjanka K., Walter, Fiona M., Chatterjee, Nilanjan, Garcia-Closas, Montserrat, Tischkowitz, Marc, Pharoah, Paul, Easton, Douglas F., Antoniou, Antonis C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group US 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6687499/
https://www.ncbi.nlm.nih.gov/pubmed/30643217
http://dx.doi.org/10.1038/s41436-018-0406-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6687499/
https://www.ncbi.nlm.nih.gov/pubmed/30643217
http://dx.doi.org/10.1038/s41436-018-0406-9

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