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Proteomic analysis reveals a role for PAX8 in peritoneal colonization of high grade serous ovarian cancer that can be targeted with micelle encapsulated thiostrepton

High grade serous ovarian cancer (HGSOC) is the fifth leading cause of cancer deaths among women yet effective targeted therapies against this disease are limited. The heterogeneity of HGSOC, including few shared oncogenic drivers and origination from both the fallopian tube epithelium (FTE) and ova...

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Detalles Bibliográficos
Autores principales: Hardy, Laura R., Pergande, Melissa R, Esparza, Karina, Heath, Kimberly N., Önyüksel, Hayat, Cologna, Stephanie M., Burdette, Joanna E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6687548/
https://www.ncbi.nlm.nih.gov/pubmed/31296958
http://dx.doi.org/10.1038/s41388-019-0842-2