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Haplotype analysis of SERPINE1 gene: Risk for aneurysmal subarachnoid hemorrhage and clinical outcomes

BACKGROUND: Aneurysmal subarachnoid hemorrhage (aSAH) has high fatality and permanent disability rates due to the severe damage to brain cells and inflammation. The SERPINE1 gene that encodes PAI‐1 for the regulation of tissue plasminogen activator is considered an important therapeutic target for a...

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Detalles Bibliográficos
Autores principales: Lin, Mingkuan, Griessenauer, Christoph J., Starke, Robert M., Tubbs, R. Shane, Shoja, Mohammadali M., Foreman, Paul M., Vyas, Nilesh A., Walters, Beverly C., Harrigan, Mark R., Hendrix, Philipp, Fisher, Winfield S., Pittet, Jean‐Francois, Mathru, Mali, Lipsky, Robert H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6687628/
https://www.ncbi.nlm.nih.gov/pubmed/31268630
http://dx.doi.org/10.1002/mgg3.737