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Structural analysis of the Aβ(11–42) amyloid fibril based on hydrophobicity distribution

The structure of the Aβ(11–42) amyloid available in PDB makes possible the molecular analysis of the specificity of amyloid formation. This molecule (PDB ID 2MVX) is the object of analysis. This work presents the outcome of in silico experiments involving various alternative conformations of the Aβ(...

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Detalles Bibliográficos
Autores principales: Roterman, Irena, Dułak, Dawid, Gadzała, Małgorzata, Banach, Mateusz, Konieczny, Leszek
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6687686/
https://www.ncbi.nlm.nih.gov/pubmed/31292794
http://dx.doi.org/10.1007/s10822-019-00209-9