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Correlation between early dynamics in circulating tumour DNA and outcome from FOLFIRI treatment in metastatic colorectal cancer

Chemotherapy resistance remains a challenge in the clinical management of metastatic colorectal cancer (mCRC). Here, early changes in cell-free circulating tumour DNA (ctDNA) levels were explored as a marker of therapeutic efficacy. Twenty-four mCRC patients were enrolled and treated with FOLFIRI ba...

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Detalles Bibliográficos
Autores principales: Lyskjær, Iben, Kronborg, Camilla Skovhus, Rasmussen, Mads Heilskov, Sørensen, Boe Sandahl, Demuth, Christina, Rosenkilde, Mona, Johansen, Amanda Frydendahl Boll, Knudsen, Michael, Vang, Søren, Krag, Søren Rasmus Palmelund, Spindler, Karen-Lise Garm, Andersen, Claus Lindbjerg
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6687711/
https://www.ncbi.nlm.nih.gov/pubmed/31395942
http://dx.doi.org/10.1038/s41598-019-47708-1