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The synergistic effects of oxaliplatin and piperlongumine on colorectal cancer are mediated by oxidative stress
Oxaliplatin-based chemotherapy is recommended as the first-line therapeutic regimen for metastatic colorectal cancer. However, long-term and repeated oxaliplatin therapy leads to drug resistance and severe adverse events, which hamper its clinical application. Thus, chemosensitizers are urgently req...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6687721/ https://www.ncbi.nlm.nih.gov/pubmed/31395855 http://dx.doi.org/10.1038/s41419-019-1824-6 |