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The synergistic effects of oxaliplatin and piperlongumine on colorectal cancer are mediated by oxidative stress

Oxaliplatin-based chemotherapy is recommended as the first-line therapeutic regimen for metastatic colorectal cancer. However, long-term and repeated oxaliplatin therapy leads to drug resistance and severe adverse events, which hamper its clinical application. Thus, chemosensitizers are urgently req...

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Detalles Bibliográficos
Autores principales: Chen, WeiQian, Lian, WeiShuai, Yuan, YiFeng, Li, MaoQuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6687721/
https://www.ncbi.nlm.nih.gov/pubmed/31395855
http://dx.doi.org/10.1038/s41419-019-1824-6