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Blood stem cell-forming haemogenic endothelium in zebrafish derives from arterial endothelium

Haematopoietic stem cells are generated from the haemogenic endothelium (HE) located in the floor of the dorsal aorta (DA). Despite being integral to arteries, it is controversial whether HE and arterial endothelium share a common lineage. Here, we present a transgenic zebrafish runx1 reporter line...

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Detalles Bibliográficos
Autores principales: Bonkhofer, Florian, Rispoli, Rossella, Pinheiro, Philip, Krecsmarik, Monika, Schneider-Swales, Janina, Tsang, Ingrid Ho Ching, de Bruijn, Marella, Monteiro, Rui, Peterkin, Tessa, Patient, Roger
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6687740/
https://www.ncbi.nlm.nih.gov/pubmed/31395869
http://dx.doi.org/10.1038/s41467-019-11423-2