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CXCR2 expression on granulocyte and macrophage progenitors under tumor conditions contributes to mo-MDSC generation via SAP18/ERK/STAT3

Myeloid-derived suppressor cells (MDSCs) comprise a critical component of the tumor environment and CXCR2 reportedly plays a key role in the pathophysiology of various inflammatory diseases. Here, CXCR2 expression on granulocyte and macrophage progenitor cells (GMPs) was found to participate in myel...

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Detalles Bibliográficos
Autores principales: Han, Xiaoqing, Shi, Huifang, Sun, Yingying, Shang, Chao, Luan, Tao, Wang, Dake, Ba, Xueqing, Zeng, Xianlu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6687752/
https://www.ncbi.nlm.nih.gov/pubmed/31395859
http://dx.doi.org/10.1038/s41419-019-1837-1