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Comprehensive transcriptomic analysis of cell lines as models of primary tumors across 22 tumor types

Cancer cell lines are a cornerstone of cancer research but previous studies have shown that not all cell lines are equal in their ability to model primary tumors. Here we present a comprehensive pan-cancer analysis utilizing transcriptomic profiles from The Cancer Genome Atlas and the Cancer Cell Li...

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Detalles Bibliográficos
Autores principales: Yu, K., Chen, B., Aran, D., Charalel, J., Yau, C., Wolf, D. M., van ‘t Veer, L. J., Butte, A. J., Goldstein, T., Sirota, M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6687785/
https://www.ncbi.nlm.nih.gov/pubmed/31395879
http://dx.doi.org/10.1038/s41467-019-11415-2