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Functional D-box sequences reset the circadian clock and drive mRNA rhythms

The circadian clock drives gene expression rhythms, leading to daily changes in physiology and behavior. In mammals, Albumin D-site-Binding Protein (DBP) rhythmically activates transcription of various genes through a DNA cis-element, D-box. The DBP-dependent transactivation is repressed by competit...

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Detalles Bibliográficos
Autores principales: Yoshitane, Hikari, Asano, Yoshimasa, Sagami, Aya, Sakai, Seinosuke, Suzuki, Yutaka, Okamura, Hitoshi, Iwasaki, Wataru, Ozaki, Haruka, Fukada, Yoshitaka
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6687812/
https://www.ncbi.nlm.nih.gov/pubmed/31428688
http://dx.doi.org/10.1038/s42003-019-0522-3