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Stimulation or Cancellation of Ca(2+) Influx by Bipolar Nanosecond Pulsed Electric Fields in Adrenal Chromaffin Cells Can Be Achieved by Tuning Pulse Waveform

Exposing adrenal chromaffin cells to single 150 to 400 ns electric pulses triggers a rise in intracellular Ca(2+) ([Ca(2+)](i)) that is due to Ca(2+) influx through voltage-gated Ca(2+) channels (VGCC) and plasma membrane electropores. Immediate delivery of a second pulse of the opposite polarity in...

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Detalles Bibliográficos
Autores principales: Bagalkot, Tarique R., Leblanc, Normand, Craviso, Gale L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6687888/
https://www.ncbi.nlm.nih.gov/pubmed/31395918
http://dx.doi.org/10.1038/s41598-019-47929-4