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Somatic mutation that affects transcription factor binding upstream of CD55 in the temporal cortex of a late-onset Alzheimer disease patient

Alzheimer’s disease (AD) is the most common neurodegenerative disease worldwide. Familial cases suggest genetic components; however, monogenetic causes are few, and the vast majority of incidences have unknown cause. Sequencing efforts have focused on germline mutations, but improved technology has...

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Detalles Bibliográficos
Autores principales: Helgadottir, Hafdis T, Lundin, Pär, Wallén Arzt, Emelie, Lindström, Anna-Karin, Graff, Caroline, Eriksson, Maria
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6688063/
https://www.ncbi.nlm.nih.gov/pubmed/31216356
http://dx.doi.org/10.1093/hmg/ddz085