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IL‐2 modulates Th2 cell responses to glucocorticosteroid: A cause of persistent type 2 inflammation?

BACKGROUND: Glucocorticosteroids (GCs) are the main treatment for asthma as they reduce type 2 cytokine expression and induce apoptosis. Asthma severity is associated with type 2 inflammation, circulating Th2 cells and higher GC requirements. OBJECTIVE: The aim of this study was to assess whether ex...

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Detalles Bibliográficos
Autores principales: Kanagalingam, Tharsan, Solomon, Lauren, Vijeyakumaran, Meerah, Palikhe, Nami Shrestha, Vliagoftis, Harissios, Cameron, Lisa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6688076/
https://www.ncbi.nlm.nih.gov/pubmed/30994266
http://dx.doi.org/10.1002/iid3.249