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Rubicon-Dependent Lc3 Recruitment to Salmonella-Containing Phagosomes Is a Host Defense Mechanism Triggered Independently From Major Bacterial Virulence Factors

Intracellular pathogens such as Salmonella depend on their molecular virulence factors to evade host defense responses like autophagy. Using a zebrafish systemic infection model, we have previously shown that phagocytes, predominantly macrophages, target Salmonella Typhimurium by an autophagy-relate...

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Detalles Bibliográficos
Autores principales: Masud, Samrah, van der Burg, Lars, Storm, Lisanne, Prajsnar, Tomasz K., Meijer, Annemarie H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6688089/
https://www.ncbi.nlm.nih.gov/pubmed/31428591
http://dx.doi.org/10.3389/fcimb.2019.00279