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The Role of Glypican-3 in Regulating Wnt, YAP, and Hedgehog in Liver Cancer
Glypican-3 (GPC3) is a cell-surface glycoprotein consisting of heparan sulfate glycosaminoglycan chains and an inner protein core. It has important functions in cellular signaling including cell growth, embryogenesis, and differentiation. GPC3 has been linked to hepatocellular carcinoma and a few ot...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2019
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6688162/ https://www.ncbi.nlm.nih.gov/pubmed/31428581 http://dx.doi.org/10.3389/fonc.2019.00708 |