LSD1 Activates PI3K/AKT Signaling Through Regulating p85 Expression in Prostate Cancer Cells

Lysine specific demethylase 1 (LSD1) functions as a transcriptional repressor through demethylating active histone marks such as mono- or di-methylated histone 3 lysine 4 (H3K4) and interacting with histone deacetylases. However, LSD1 can also act as an activator through demethylating repressive his...

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Detalles Bibliográficos
Autores principales: Wang, Zifeng, Gao, Shuai, Han, Dong, Han, Wanting, Li, Muqing, Cai, Changmeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Oncology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6688199/
https://www.ncbi.nlm.nih.gov/pubmed/31428587
http://dx.doi.org/10.3389/fonc.2019.00721

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6688199/
https://www.ncbi.nlm.nih.gov/pubmed/31428587
http://dx.doi.org/10.3389/fonc.2019.00721

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