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Differentiation of adipose-derived stem cells to functional CD105(neg) CD73(low) melanocyte precursors guided by defined culture condition

BACKGROUND: The generation of functional human epidermal melanocytes (HEM) from stem cells provides an unprecedented source for cell-based therapy in vitiligo. Despite the important efforts exerted to obtain melanin-producing cells from stem cells, pre-clinical results still lack the safety and scal...

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Detalles Bibliográficos
Autores principales: Zavala, Gabriela, Sandoval, Carolina, Meza, Daniel, Contreras, Rafael, Gubelin, Walter, Khoury, Maroun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6688240/
https://www.ncbi.nlm.nih.gov/pubmed/31399041
http://dx.doi.org/10.1186/s13287-019-1364-0