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Neuroinflammatory astrocytes generated from cord blood-derived human induced pluripotent stem cells
BACKGROUND: Astrocytes respond to central nervous system (CNS) injury and disease by transforming to a reactive astrogliosis cell state that can contribute to either CNS dysfunction or repair. Neuroinflammation is a powerful driver of a harmful A1 astrogliosis phenotype associated with in vitro neur...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6688278/ https://www.ncbi.nlm.nih.gov/pubmed/31395092 http://dx.doi.org/10.1186/s12974-019-1553-x |