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Neuroinflammatory astrocytes generated from cord blood-derived human induced pluripotent stem cells

BACKGROUND: Astrocytes respond to central nervous system (CNS) injury and disease by transforming to a reactive astrogliosis cell state that can contribute to either CNS dysfunction or repair. Neuroinflammation is a powerful driver of a harmful A1 astrogliosis phenotype associated with in vitro neur...

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Detalles Bibliográficos
Autores principales: Zhou, Qiong, Viollet, Coralie, Efthymiou, Anastasia, Khayrullina, Guzal, Moritz, Kasey E., Wilkerson, Matthew D., Sukumar, Gauthaman, Dalgard, Clifton L., Doughty, Martin L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6688278/
https://www.ncbi.nlm.nih.gov/pubmed/31395092
http://dx.doi.org/10.1186/s12974-019-1553-x