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Epigenetic and non-epigenetic mode of SIRT1 action during oocyte meiosis progression

BACKGROUND: SIRT1 histone deacetylase acts on many epigenetic and non-epigenetic targets. It is thought that SIRT1 is involved in oocyte maturation; therefore, the importance of the ooplasmic SIRT1 pool for the further fate of mature oocytes has been strongly suggested. We hypothesised that SIRT1 pl...

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Detalles Bibliográficos
Autores principales: Nevoral, Jan, Landsmann, Lukas, Stiavnicka, Miriam, Hosek, Petr, Moravec, Jiri, Prokesova, Sarka, Rimnacova, Hedvika, Koutna, Eliska, Klein, Pavel, Hoskova, Kristyna, Zalmanova, Tereza, Fenclova, Tereza, Petr, Jaroslav, Kralickova, Milena
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6688279/
https://www.ncbi.nlm.nih.gov/pubmed/31413827
http://dx.doi.org/10.1186/s40104-019-0372-3