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Glutamine Metabolism Drives Growth in Advanced Hormone Receptor Positive Breast Cancer

Dependence on the glutamine pathway is increased in advanced breast cancer cell models and tumors regardless of hormone receptor status or function. While 70% of breast cancers are estrogen receptor positive (ER+) and depend on estrogen signaling for growth, advanced ER+ breast cancers grow independ...

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Detalles Bibliográficos
Autores principales: Demas, Diane M., Demo, Susan, Fallah, Yassi, Clarke, Robert, Nephew, Kenneth P., Althouse, Sandra, Sandusky, George, He, Wei, Shajahan-Haq, Ayesha N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6688514/
https://www.ncbi.nlm.nih.gov/pubmed/31428575
http://dx.doi.org/10.3389/fonc.2019.00686