Cargando…
Glutamine Metabolism Drives Growth in Advanced Hormone Receptor Positive Breast Cancer
Dependence on the glutamine pathway is increased in advanced breast cancer cell models and tumors regardless of hormone receptor status or function. While 70% of breast cancers are estrogen receptor positive (ER+) and depend on estrogen signaling for growth, advanced ER+ breast cancers grow independ...
Autores principales: | Demas, Diane M., Demo, Susan, Fallah, Yassi, Clarke, Robert, Nephew, Kenneth P., Althouse, Sandra, Sandusky, George, He, Wei, Shajahan-Haq, Ayesha N. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2019
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6688514/ https://www.ncbi.nlm.nih.gov/pubmed/31428575 http://dx.doi.org/10.3389/fonc.2019.00686 |
Ejemplares similares
-
Targeting WEE1 Inhibits Growth of Breast Cancer Cells That Are Resistant to Endocrine Therapy and CDK4/6 Inhibitors
por: Fallah, Yassi, et al.
Publicado: (2021) -
Glutamine metabolism and the unfolded protein response in MYC-driven breast cancer
por: Shajahan-Haq, Ayesha, et al.
Publicado: (2014) -
MYC-Driven Pathways in Breast Cancer Subtypes
por: Fallah, Yassi, et al.
Publicado: (2017) -
MYC regulates the unfolded protein response and glucose and glutamine uptake in endocrine resistant breast cancer
por: Shajahan-Haq, Ayesha N, et al.
Publicado: (2014) -
Modeling breast cancer proliferation, drug synergies, and alternating therapies
por: He, Wei, et al.
Publicado: (2023)