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N-Substituted Pyrrole Derivative 12m Inhibits HIV-1 Entry by Targeting Gp41 of HIV-1 Envelope Glycoprotein

The combination of three or more antiviral agents that act on different targets is known as highly active antiretroviral therapy (HAART), which is widely used to control HIV infection. However, because drug resistance and adverse effects occur after long-term administration, an increasing number of...

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Detalles Bibliográficos
Autores principales: Qiu, Jiayin, Liang, Taizhen, Wu, Junyan, Yu, Fei, He, Xiaoyang, Tian, Yuanxin, Xie, Lan, Jiang, Shibo, Liu, Shuwen, Li, Lin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6688628/
https://www.ncbi.nlm.nih.gov/pubmed/31427969
http://dx.doi.org/10.3389/fphar.2019.00859