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Insulin-Mediated Changes in Tau Hyperphosphorylation and Autophagy in a Drosophila Model of Tauopathy and Neuroblastoma Cells

Almost 50 million people in the world are affected by dementia; the most prevalent form of which is Alzheimer’s disease (AD). Although aging is considered to be the main risk factor for AD, growing evidence from epidemiological studies suggests that type 2 diabetes mellitus (T2DM) increases the risk...

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Detalles Bibliográficos
Autores principales: Chatterjee, Shreyasi, Ambegaokar, Suren. S., Jackson, George R., Mudher, Amritpal
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6688711/
https://www.ncbi.nlm.nih.gov/pubmed/31427921
http://dx.doi.org/10.3389/fnins.2019.00801