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Selegiline Recovers Synaptic Plasticity in the Medial Prefrontal Cortex and Improves Corresponding Depression-Like Behavior in a Mouse Model of Parkinson’s Disease

In patients with Parkinson’s disease (PD), non-motor symptoms (NMS) including depression and anxiety are often recognized before motor symptoms develop. Monoamine oxidase (MAO)-B inhibitors are therapeutically effective for motor symptoms; however, their effects on NMS in PD are yet to be fully asse...

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Detalles Bibliográficos
Autores principales: Okano, Motoki, Takahata, Kazue, Sugimoto, Junya, Muraoka, Shizuko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6688712/
https://www.ncbi.nlm.nih.gov/pubmed/31427934
http://dx.doi.org/10.3389/fnbeh.2019.00176