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Single-cell transcriptome analysis of CD8 (+) T-cell memory inflation

Background: Persistent viruses such as murine cytomegalovirus (MCMV) and adenovirus-based vaccines induce strong, sustained CD8 (+) T-cell responses, described as memory “inflation”. These retain functionality, home to peripheral organs and are associated with a distinct transcriptional program. Met...

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Detalles Bibliográficos
Autores principales: Highton, Andrew J., Zinser, Madeleine E., Lee, Lian Ni, Hutchings, Claire L., De Lara, Catherine, Phetsouphanh, Chansavath, Willberg, Chris B., Gordon, Claire L., Klenerman, Paul, Marchi, Emanuele
Formato: Online Artículo Texto
Lenguaje:English
Publicado: F1000 Research Limited 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6688724/
https://www.ncbi.nlm.nih.gov/pubmed/31448339
http://dx.doi.org/10.12688/wellcomeopenres.15115.1