Membrane Recognition and Binding by the Phosphatidylinositol Phosphate Kinase PIP5K1A: A Multiscale Simulation Study

Phosphatidylinositol phosphates (PIPs) are lipid signaling molecules that play key roles in many cellular processes. PIP5K1A kinase catalyzes phosphorylation of PI4P to form PIP(2), which in turn interacts with membrane and membrane-associated proteins. We explore the mechanism of membrane binding b...

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Detalles Bibliográficos
Autores principales: Amos, Sarah-Beth T.A., Kalli, Antreas C., Shi, Jiye, Sansom, Mark S.P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6688827/
https://www.ncbi.nlm.nih.gov/pubmed/31204251
http://dx.doi.org/10.1016/j.str.2019.05.004

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6688827/
https://www.ncbi.nlm.nih.gov/pubmed/31204251
http://dx.doi.org/10.1016/j.str.2019.05.004

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