Single-cell landscape in mammary epithelium reveals bipotent-like cells associated with breast cancer risk and outcome

Adult stem-cells may serve as the cell-of-origin for cancer, yet their unbiased identification in single cell RNA sequencing data is challenging due to the high dropout rate. In the case of breast, the existence of a bipotent stem-like state is also controversial. Here we apply a marker-free algorit...

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Detalles Bibliográficos
Autores principales: Chen, Weiyan, Morabito, Samuel J., Kessenbrock, Kai, Enver, Tariq, Meyer, Kerstin B., Teschendorff, Andrew E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6689007/
https://www.ncbi.nlm.nih.gov/pubmed/31428694
http://dx.doi.org/10.1038/s42003-019-0554-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6689007/
https://www.ncbi.nlm.nih.gov/pubmed/31428694
http://dx.doi.org/10.1038/s42003-019-0554-8

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