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Single-cell landscape in mammary epithelium reveals bipotent-like cells associated with breast cancer risk and outcome
Adult stem-cells may serve as the cell-of-origin for cancer, yet their unbiased identification in single cell RNA sequencing data is challenging due to the high dropout rate. In the case of breast, the existence of a bipotent stem-like state is also controversial. Here we apply a marker-free algorit...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2019
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6689007/ https://www.ncbi.nlm.nih.gov/pubmed/31428694 http://dx.doi.org/10.1038/s42003-019-0554-8 |