A STAT3-based gene signature stratifies glioma patients for targeted therapy

Intratumoral heterogeneity is a hallmark of glioblastoma (GBM) tumors, thought to negatively influence therapeutic outcome. Previous studies showed that mesenchymal tumors have a worse outcome than the proneural subtype. Here we focus on STAT3 as its activation precedes the proneural-mesenchymal tra...

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Detalles Bibliográficos
Autores principales: Tan, Melanie Si Yan, Sandanaraj, Edwin, Chong, Yuk Kien, Lim, See Wee, Koh, Lynnette Wei Hsien, Ng, Wai Hoe, Tan, Nguan Soon, Tan, Patrick, Ang, Beng Ti, Tang, Carol
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6689009/
https://www.ncbi.nlm.nih.gov/pubmed/31399589
http://dx.doi.org/10.1038/s41467-019-11614-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6689009/
https://www.ncbi.nlm.nih.gov/pubmed/31399589
http://dx.doi.org/10.1038/s41467-019-11614-x

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