Effects of PDE-5 Inhibition on the Cardiopulmonary System After 2 or 4 Weeks of Chronic Hypoxia

PURPOSE: In pulmonary hypertension (PH), hypoxia represents both an outcome and a cause of exacerbation. We addressed the question whether hypoxia adaptation might affect the mechanisms underlying PH alleviation through phosphodiesterase-5 (PDE5) inhibition. METHODS: Eight-week-old male Sprague-Dawl...

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Detalles Bibliográficos
Autores principales: Nydegger, Coline, Corno, Antonio F., von Segesser, Ludwig K., Beghetti, Maurice, Samaja, Michele, Milano, Giuseppina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2019
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6689028/
https://www.ncbi.nlm.nih.gov/pubmed/31264002
http://dx.doi.org/10.1007/s10557-019-06887-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6689028/
https://www.ncbi.nlm.nih.gov/pubmed/31264002
http://dx.doi.org/10.1007/s10557-019-06887-9

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