The pause-initiation limit restricts transcription activation in human cells

Eukaryotic gene transcription is often controlled at the level of RNA polymerase II (Pol II) pausing in the promoter-proximal region. Pausing Pol II limits the frequency of transcription initiation (‘pause-initiation limit’), predicting that the pause duration must be decreased for transcriptional a...

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Detalles Bibliográficos
Autores principales: Gressel, Saskia, Schwalb, Björn, Cramer, Patrick
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6689055/
https://www.ncbi.nlm.nih.gov/pubmed/31399571
http://dx.doi.org/10.1038/s41467-019-11536-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6689055/
https://www.ncbi.nlm.nih.gov/pubmed/31399571
http://dx.doi.org/10.1038/s41467-019-11536-8

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