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MMP12 Inhibits Corneal Neovascularization and Inflammation through Regulation of CCL2

Following corneal injury, coordinated cellular and protein interactions occur at the wound site to restore tissue homeostasis. Regulation of this response is required to prevent the development of chronic inflammation, abnormal neovascularization, and fibrosis. The chemokine CCL2 and its primary rec...

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Detalles Bibliográficos
Autores principales: Wolf, Marie, Clay, Selene M., Zheng, Siyu, Pan, Peipei, Chan, Matilda F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6689067/
https://www.ncbi.nlm.nih.gov/pubmed/31399604
http://dx.doi.org/10.1038/s41598-019-47831-z