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Genetic risk for autoimmunity is associated with distinct changes in the human gut microbiome

Susceptibility to many human autoimmune diseases is under strong genetic control by class II human leukocyte antigen (HLA) allele combinations. These genes remain by far the greatest risk factors in the development of type 1 diabetes and celiac disease. Despite this, little is known about HLA influe...

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Detalles Bibliográficos
Autores principales: Russell, Jordan T., Roesch, Luiz F. W., Ördberg, Malin, Ilonen, Jorma, Atkinson, Mark A., Schatz, Desmond A., Triplett, Eric W., Ludvigsson, Johnny
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6689114/
https://www.ncbi.nlm.nih.gov/pubmed/31399563
http://dx.doi.org/10.1038/s41467-019-11460-x