Orcinol glucoside facilitates the shift of MSC fate to osteoblast and prevents adipogenesis via Wnt/β-catenin signaling pathway

BACKGROUND: During osteoporosis, bone mesenchymal stem cells (BMSCs) lineage commitment shifts to adipocytes, causing fat accumulation and bone loss in the skeleton. Seeking drugs that could reverse the adipocyte fate determination of BMSCs is critical for osteoporosis therapy. As a traditional Chin...

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Detalles Bibliográficos
Autores principales: Zhou, Xinying, Liu, Zezheng, Huang, Bin, Yan, Huibo, Yang, Changsheng, Li, Qingchu, Jin, Dadi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2019
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6689118/
https://www.ncbi.nlm.nih.gov/pubmed/31496649
http://dx.doi.org/10.2147/DDDT.S208458

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6689118/
https://www.ncbi.nlm.nih.gov/pubmed/31496649
http://dx.doi.org/10.2147/DDDT.S208458

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