EDNRB isoform 3 confers Temozolomide resistance in A375 melanoma cells by modulating membrane potential, reactive oxygen species and mitochondrial Ca(2+)

BACKGROUND: The role of endothelin receptor type B (EDNRB) isoform 3 involved in Temozolomide (TMZ)-induced melanoma cell death has not yet been elucidated. METHODS: The subcellular localization of EDNRB isoform 3 was determined by confocal and immunoblotting assays. Silencing EDNRB isoform 3 was pe...

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Detalles Bibliográficos
Autores principales: Chen, Yun Shan, Liu, Fen, Luo, Yi Hong, Fan, Yue, Xu, Fang Gui, Li, Pin, Zhou, Bei, Pan, Xiu Yu, Wang, Chi Chiu, Cui, Long
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2019
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6689146/
https://www.ncbi.nlm.nih.gov/pubmed/31496797
http://dx.doi.org/10.2147/CMAR.S208604

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6689146/
https://www.ncbi.nlm.nih.gov/pubmed/31496797
http://dx.doi.org/10.2147/CMAR.S208604

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