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L-655,708 Does not Prevent Isoflurane-induced Memory Deficits in Old Mice
BACKGROUND: General anesthesia and increasing age are two main risk factors for postoperative cognitive dysfunction (POCD). Effective agents for the prevention or treatment of POCD are urgently needed. L-655,708, an inverse agonist of α5 subunit-containing γ-aminobutyric acid subtype A (α5GABA(A)) r...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
De Gruyter
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6689210/ https://www.ncbi.nlm.nih.gov/pubmed/31410301 http://dx.doi.org/10.1515/tnsci-2019-0032 |