Clonal replacement of tumor-specific T cells following PD-1 blockade

Immunotherapies that block inhibitory checkpoint receptors on T cells have transformed the clinical care of cancer patients(1). However, whether the T cell response to checkpoint blockade relies on reinvigoration of pre-existing tumor infiltrating T cells (TILs) or on recruitment of novel T cells re...

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Detalles Bibliográficos
Autores principales: Yost, Kathryn E., Satpathy, Ansuman T., Wells, Daniel K., Qi, Yanyan, Wang, Chunlin, Kageyama, Robin, McNamara, Katherine, Granja, Jeffrey M., Sarin, Kavita Y., Brown, Ryanne A., Gupta, Rohit K., Curtis, Christina, Bucktrout, Samantha L., Davis, Mark M., Chang, Anne Lynn S., Chang, Howard Y.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6689255/
https://www.ncbi.nlm.nih.gov/pubmed/31359002
http://dx.doi.org/10.1038/s41591-019-0522-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6689255/
https://www.ncbi.nlm.nih.gov/pubmed/31359002
http://dx.doi.org/10.1038/s41591-019-0522-3

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