Cargando…

Clonal replacement of tumor-specific T cells following PD-1 blockade

Immunotherapies that block inhibitory checkpoint receptors on T cells have transformed the clinical care of cancer patients(1). However, whether the T cell response to checkpoint blockade relies on reinvigoration of pre-existing tumor infiltrating T cells (TILs) or on recruitment of novel T cells re...

Descripción completa

Detalles Bibliográficos
Autores principales:	Yost, Kathryn E., Satpathy, Ansuman T., Wells, Daniel K., Qi, Yanyan, Wang, Chunlin, Kageyama, Robin, McNamara, Katherine, Granja, Jeffrey M., Sarin, Kavita Y., Brown, Ryanne A., Gupta, Rohit K., Curtis, Christina, Bucktrout, Samantha L., Davis, Mark M., Chang, Anne Lynn S., Chang, Howard Y.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	2019
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6689255/ https://www.ncbi.nlm.nih.gov/pubmed/31359002 http://dx.doi.org/10.1038/s41591-019-0522-3

Ejemplares similares

Expression of the transcription factor ZBTB46 distinguishes human histiocytic disorders of classical dendritic cell origin
por: Satpathy, Ansuman T., et al.
Publicado: (2018)

Systemic Anti–PD-1 Immunotherapy Results in PD-1 Blockade on T Cells in the Cerebrospinal Fluid
por: Portnow, Jana, et al.
Publicado: (2020)

Clonal replacement of novel T cells: a new phenomenon in the tumor microenvironment following PD-1 blockade
por: Li, Xue, et al.
Publicado: (2019)

Chromatin Landscape Underpinning Human Dendritic Cell Heterogeneity
por: Leylek, Rebecca, et al.
Publicado: (2020)

Human B cell clonal expansion and convergent antibody responses to SARS CoV-2
por: Nielsen, Sandra C. A., et al.
Publicado: (2020)

Pembrolizumab for advanced basal cell carcinoma: An investigator-initiated, proof-of-concept study
por: Chang, Anne Lynn S., et al.
Publicado: (2018)

Resistance Mechanism of PD-1/PD-L1 Blockade in the Cancer-Immunity Cycle
por: Zhuang, Yuan, et al.
Publicado: (2020)

Ipilimumab alone or in combination with nivolumab in patients with advanced melanoma who have progressed or relapsed on PD-1 blockade: clinical outcomes and translational biomarker analyses
por: Friedman, Claire F, et al.
Publicado: (2022)

Impaired mitochondrial oxidative phosphorylation limits the self-renewal of T cells exposed to persistent antigen
por: Vardhana, Santosha A., et al.
Publicado: (2020)

Human B Cell Clonal Expansion and Convergent Antibody Responses to SARS-CoV-2
por: Nielsen, Sandra C.A., et al.
Publicado: (2020)

Clonal hematopoiesis is associated with protection from Alzheimer’s disease
por: Bouzid, Hind, et al.
Publicado: (2023)

Impact of Intervention Measures on MRSA Clonal Type and Carriage Site Prevalence
por: Cassone, Marco, et al.
Publicado: (2016)

Integrative analysis of single-cell genomics data by coupled nonnegative matrix factorizations
por: Duren, Zhana, et al.
Publicado: (2018)

An update on immunotherapy with PD-1 and PD-L1 blockade
por: Koh, Sung Ae
Publicado: (2021)

PD-1/PD-L1 Blockade: Have We Found the Key to Unleash the Antitumor Immune Response?
por: Xu-Monette, Zijun Y., et al.
Publicado: (2017)

Clonal tracing reveals diverse patterns of response to immune checkpoint blockade
por: Gu, Shengqing Stan, et al.
Publicado: (2020)

Localized PD-1 Blockade in a Mouse Model of Renal Cell Carcinoma
por: Pham, Ngoc B., et al.
Publicado: (2022)

Blockade of PD-1 immunosuppression boosts CAR T-cell therapy
por: John, Liza B, et al.
Publicado: (2013)

CTLA-4 and PD-1 Pathway Blockade: Combinations in the Clinic
por: Callahan, Margaret K., et al.
Publicado: (2015)

Human Cancer Immunotherapy with PD-1/PD-L1 Blockade
por: Zheng, Peilin, et al.
Publicado: (2015)

Genetic biomarkers for PD-1/PD-L1 blockade therapy
por: Kataoka, Keisuke, et al.
Publicado: (2016)

Potential Biomarkers for the Efficacy of PD-1-PD-L Blockade in Cancer
por: Grecea, Miruna, et al.
Publicado: (2021)

Management of Thyrotoxicosis Induced by PD1 or PD-L1 Blockade
por: Brancatella, Alessandro, et al.
Publicado: (2021)

Management of Thyrotoxicosis Induced by PD1 or PD-L1 Blockade
por: Brancatella, Alessandro, et al.
Publicado: (2021)

Further investigation of blockade effects and binding affinities of selected natural compounds to immune checkpoint PD-1/PD-L1
por: Li, Huifang, et al.
Publicado: (2022)

Establishment of Human PD-1/PD-L1 Blockade Assay Based on Surface Plasmon Resonance (SPR) Biosensor
por: Puopolo, Tess, et al.
Publicado: (2023)

Application of PD-1 Blockade in Cancer Immunotherapy
por: Wu, Xiaomo, et al.
Publicado: (2019)

PD-1 Blockade in Anaplastic Thyroid Carcinoma
por: Capdevila, Jaume, et al.
Publicado: (2020)

Biomarkers of response to PD-1 pathway blockade
por: Li, Hanxiao, et al.
Publicado: (2022)

Chromatin accessibility landscapes of skin cells in systemic sclerosis nominate dendritic cells in disease pathogenesis
por: Liu, Qian, et al.
Publicado: (2020)

Dynamic chromatin regulatory landscape of human CAR T cell exhaustion
por: Gennert, David G., et al.
Publicado: (2021)

Regulation of PD-1/PD-L1 pathway and resistance to PD-1/PD-L1 blockade
por: Bai, Jie, et al.
Publicado: (2017)

Author Correction: Chromatin accessibility landscapes of skin cells in systemic sclerosis nominate dendritic cells in disease pathogenesis
por: Liu, Qian, et al.
Publicado: (2020)

PD-1/PD-L1 blockade in cancer treatment: perspectives and issues
por: Hamanishi, Junzo, et al.
Publicado: (2016)

Oncolytic virus and PD-1/PD-L1 blockade combination therapy
por: Chen, Chun-Yu, et al.
Publicado: (2018)

Drug response to PD-1/PD-L1 blockade: based on biomarkers
por: Chen, Qi, et al.
Publicado: (2018)

Efficacy of PD-1/PD-L1 blockade monotherapy in clinical trials
por: Zhao, Bin, et al.
Publicado: (2020)

Is There a Place for PD-1-PD-L Blockade in Acute Myeloid Leukemia?
por: Jimbu, Laura, et al.
Publicado: (2021)

Clinical PD-1/PD-L1 Blockades in Combination Therapies for Lymphomas
por: Katsuya, Hiroo, et al.
Publicado: (2023)

Clonal evolution of leukemia from G6PD studies
por: Bacharach, Tal, et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_leovshp34r1fil7us2ldi719k4