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GM-CSF and CXCR4 Define a T Helper Cell Signature in Multiple Sclerosis

Cytokine dysregulation is a central driver of chronic inflammatory diseases such as multiple sclerosis (MS). Here we sought to determine the characteristic cellular and cytokine polarization profile in patients with relapsing-remitting multiple sclerosis (RRMS) by high-dimensional single-cell mass c...

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Detalles Bibliográficos
Autores principales: Galli, Edoardo, Hartmann, Felix J., Schreiner, Bettina, Ingelfinger, Florian, Arvaniti, Eirini, Diebold, Martin, Mrdjen, Dunja, van der Meer, Franziska, Krieg, Carsten, Al Nimer, Faiez, Sanderson, Nicholas, Stadelmann, Christine, Khademi, Mohsen, Piehl, Fredrik, Claassen, Manfred, Derfuss, Tobias, Olsson, Tomas, Becher, Burkhard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6689469/
https://www.ncbi.nlm.nih.gov/pubmed/31332391
http://dx.doi.org/10.1038/s41591-019-0521-4