Computational evaluation of natural compounds as potential inhibitors of human PEPCK-M: an alternative for lung cancer therapy

BACKGROUND: Lung cancer is the leading cause of cancer-related death worldwide. Among its subtypes, non-small cell lung cancer (NSCLC) is the most common. Recently, the mitochondrial isoform of the enzyme phosphoenolpyruvate carboxykinase (HsPEPCK-M) was identified as responsible for the metabolic a...

Descripción completa

Detalles Bibliográficos
Autores principales: Baptista, Luiz Phillippe R, Sinatti, Vanessa VC, Da Silva, Joao HM, Dardenne, Laurent Emmanuel, Guimarães, Ana Carolina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2019
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6689533/
https://www.ncbi.nlm.nih.gov/pubmed/31496750
http://dx.doi.org/10.2147/AABC.S197119

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6689533/
https://www.ncbi.nlm.nih.gov/pubmed/31496750
http://dx.doi.org/10.2147/AABC.S197119

Ejemplares similares