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Computational evaluation of natural compounds as potential inhibitors of human PEPCK-M: an alternative for lung cancer therapy

BACKGROUND: Lung cancer is the leading cause of cancer-related death worldwide. Among its subtypes, non-small cell lung cancer (NSCLC) is the most common. Recently, the mitochondrial isoform of the enzyme phosphoenolpyruvate carboxykinase (HsPEPCK-M) was identified as responsible for the metabolic a...

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Detalles Bibliográficos
Autores principales:	Baptista, Luiz Phillippe R, Sinatti, Vanessa VC, Da Silva, Joao HM, Dardenne, Laurent Emmanuel, Guimarães, Ana Carolina
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Dove 2019
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6689533/ https://www.ncbi.nlm.nih.gov/pubmed/31496750 http://dx.doi.org/10.2147/AABC.S197119

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